*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK9710000
CHEMICAL NAME           : Piperazine,
                          1,4-bis(2-(2-methyl-1,3-benzodioxol-2-yl)ethyl))-
CAS REGISTRY NUMBER     : 64516-33-2
BEILSTEIN REFERENCE NO. : 0583739
REFERENCE               : 5-23-02-00535 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H30-N2-O4
MOLECULAR WEIGHT        : 410.56
WISWESSER LINE NOTATION : T56 BO DO CHJ C1 C2- AT6N DNTJ D2- CT56 BO DO CHJ C1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-(Bis(2-(2-methyl-1,3-benzodioxol-2-yl)ethyl))piperazine
   * 1,4-Di-((2-methyl-1,3-benzodioxol-2-yl)ethyl)piperazine
   * LR 623
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,413,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,413,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 226,286,1977
 
                            *** END OF RECORD ***