*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK9186400
CHEMICAL NAME           : Piperazine,
                          4-(4,4-bis(p-fluorophenyl)butyl)-1-(2-(4'-phenylcyclo
                          hexylamino)ethyl)-, trihydrochloride, (E)-
CAS REGISTRY NUMBER     : 63698-38-4
LAST UPDATED            : 199201
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C34-H43-F2-N3.3Cl-H
MOLECULAR WEIGHT        : 641.18
WISWESSER LINE NOTATION : T6N DNTJ A3YR DF&R DF& D2M- AL6TJ DR &GH 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   trans-4-(4,4-Bis(p-fluorophenyl)butyl)-1-(2-(4'-phenylcyclohexylamino)et
     hyl)piperazine 3HCl
   * M.G. 18001-3HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 389 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 32,461,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 32,461,1977
 
                            *** END OF RECORD ***