*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK8043000
CHEMICAL NAME           : Piperazine,
                          1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dich
                          loro-4-(2-thienylcarb onyl) phenoxy)acetyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 122001-64-3
LAST UPDATED            : 199212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C27-H25-Cl2-N5-O5-S.Cl-H
MOLECULAR WEIGHT        : 638.99
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARPMAS Archiv der Pharmazie (Weinheim, Germany)  (VCH Pub., Inc., 303 NW
   12th Ave., Deerfield Beach, FL 33441)  V.51-261, 1835-1923; V.305-    1972-
   Volume(issue)/page/year: 322,359,1989
 
                            *** END OF RECORD ***