*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7919100
CHEMICAL NAME           : Piperazine, 1-(1-adamantyl)-4-cyclooctyl-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 62936-27-0
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H38-N2.2Cl-H
MOLECULAR WEIGHT        : 403.54
WISWESSER LINE NOTATION : L66 B6/B-H/DI/ A B- C 1B ITJ B- AT6N DNTJ D- AL8TJ
                          &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adamantane, 1-(1-(4-cyclooctyl)piperazinyl)-, dihydrochloride
   * 1-(1-Adamantyl)-4-cyclooctylpiperazine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,355,1977
 
                            *** END OF RECORD ***