*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7912500
CHEMICAL NAME           : Piperazine, 1-acetyl-2,6-dimethyl-4-nitroso-
CAS REGISTRY NUMBER     : 75881-17-3
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H15-N3-O2
MOLECULAR WEIGHT        : 185.26
WISWESSER LINE NOTATION : T6N DNTJ AV1 B1 DNO F1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1-Acetyl-4-nitroso-2,6-dimethylpiperazine
   * 1-Nitroso-4-acetyl-3,5-dimethylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1950 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   41,1034,1981
 
                            *** END OF RECORD ***