*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7801600
CHEMICAL NAME           : 1-Piperazineacetamide,
                          N-(5,11-dihydro(1)benzoxepino(3,4-b)pyridin-5-yl)-4-m
                          ethyl-, (E)-2-butenedioate, hydrate (2:2:3)
CAS REGISTRY NUMBER     : 95968-43-7
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-N4-O2.C4-H4-O4.3/2H2-O
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5,11-Dihydro-5-((4-methyl-1-piperazinyl)acetyl)amino(1)benzoxepino(3,4-b
     )pyridine fumarate H2O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0129879
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0129879
 
                            *** END OF RECORD ***