*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7791000
CHEMICAL NAME           : 1-Piperazinamine,
                          4-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-N
                          -((4-(2-
                          (dimethylamino)ethoxy)-3-ethoxyphenyl)methylene)-,
                          dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 86759-10-6
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C31-H37-Cl-N4-O2-S.2Cl-H.H2-O
MOLECULAR WEIGHT        : 655.16
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 48,1173,1983
 
                            *** END OF RECORD ***