*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TH9200000
CHEMICAL NAME           : 1(2H)-Phthalazinone,
                          4-benzyl-2-(2-(dimethylamino)ethyl)-, hydrochloride
CAS REGISTRY NUMBER     : 16188-76-4
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H21-N3-O.Cl-H
MOLECULAR WEIGHT        : 343.89
WISWESSER LINE NOTATION : T66 BVNNJ C2N1&1 E1R &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ahanon
   * 4-Benzyl-2-(2-(dimethylamino)ethyl)-1(2H)-phthalazinone hydrochloride
   * HL 2186
   * Talastine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 116 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,678,1957
 
                            *** END OF RECORD ***