*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TH8575000
CHEMICAL NAME           : Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)-
CAS REGISTRY NUMBER     : 85-73-4
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C17-H13-N3-O5-S2
MOLECULAR WEIGHT        : 403.45
WISWESSER LINE NOTATION : T5N CSJ BMSWR DMVR BVQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AFI-Ftalyl
   * (o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole
   * Cremothalidine
   * Enteramida
   * Entero-sulfina
   * Entexidin
   * Entexidina
   * Ftalazol
   * Ftalylsulfathiazol
   * Intestiazol
   * Phthalazol
   * Phthalazole
   * Phthaloylsulfathiazole
   * 2-(N(sup 4)-Phthalyaminobenzenesulfonamide)thiazole
   * 2-(N(sup 4)-Phthalyaminobenzenesulfonamido)thiazole
   * 2-(p-Phthalylaminobenzenesulfamido)thiazole
   * Phthalylnorsulfazole
   * 2-(N(sup 4)-Phthalylsulfanilamido)thiazole
   * 2-(p-N-Phthalylsulfanilyl)aminothiazole
   * Phthalylsulfathiazole
   * Phthalylsulfonazole
   * Phthalylsulphathiazole
   * Sulfacetil
   * Sulfanilamide, N(sup 4)-(o-carboxybenzoyl)-N'-2-thiazolyl-
   * Sulfaphthalazole
   * Sulfathalidine
   * Sulftalyl
   * Taleudron
   * Talidine
   * Taloudron
   * Thalazole
   * Thalistanin
   * Thalistatyl
   * 4'-(2-Thiazolylsulfamoyl)phthalanilic acid
   * 4'-(2-Thiazolylsulfamyl)phthalanilic acid
   * Ultratiazol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 58(12),9,1993
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,116,1944
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 920 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,116,1944
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12900 mg/kg/30D-I
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of esophagus
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 58(12),9,1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 84641
       No. of Facilities: 193 (estimated)
       No. of Industries: 2
       No. of Occupations: 6
       No. of Employees: 9471 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84641
       No. of Facilities: 16 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 94 (estimated)
       No. of Female Employees: 62 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***