*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TG1650000
CHEMICAL NAME           : Phosphorothioic acid, O-(2-(ethylthio)ethyl)
                          O,O-dimethyl ester
CAS REGISTRY NUMBER     : 867-27-6
BEILSTEIN REFERENCE NO. : 1707378
REFERENCE               : 4-01-00-02445 (Beilstein Handbook Reference)
LAST UPDATED            : 199707
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C6-H15-O3-P-S2
MOLECULAR WEIGHT        : 230.30
WISWESSER LINE NOTATION : 2S2OPS&O1&O1
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * Demeton-O-methyl
   * Demeton-O-metile
   * O,O-Dimethyl-O-(2-aethylthio-aethyl)monothiophosphat
   * O,O-Dimethyl 2-ethylmercaptoethyl thiophosphate, thiono isomer
   * O,O-Dimethyl-O-(2-ethyl-thio-ethyl)-monothiofosfaat
   * O,O-Dimethyl O-ethylmercaptoethyl thiophosphate
   * O,O-Dimethyl O-2-(ethylthio)ethyl phosphorothioate
   * O,O-Dimetil-O-(2-etiltio-etil)-monotiofosfato
   * Ethanol, 2-(ethylthio)-, O-ester with O,O-dimethyl phosphorothioate
   * beta-Ethylmercaptoethyl dimethyl thionophosphate
   * O-(2-(Ethylthio)ethyl) O,O-dimethyl phosphorothioate
   * 2-(Ethylthio)ethyl dimethyl phosphorothionate
   * Methyl-demeton-O
   * O-Methyldemeton
   * Thiophosphate de O,O-dimethyle et de O-2-ethylthio-ethyle
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 22,559,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 216 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way, Colchester, Essex CO2 8HP, UK)  V.1-    1906- Volume(issue)/page/year:
   67,187,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 46 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 22,559,1959
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 22,559,1959
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 20 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 28(3),21,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 22,559,1959

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   RREVAH Residue Reviews.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.1-    1962-  Volume(issue)/page/year:
   46,1,1973

   TOXICOLOGY REVIEW
   MZUZA8 Meditsinskii Zhurnal Uzbekistana.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR) No.1-    1957-  Volume(issue)/page/year: (8),90,1973

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-DENMARK:TWA 0.05 ppm (0.5 mg/m3);Skin JAN 1993

 
                            *** END OF RECORD ***