*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TG1380000
CHEMICAL NAME           : Phosphorothioic acid, O-ethyl S-propyl
                          O-(2,4,6-trichlorophenyl) ester
CAS REGISTRY NUMBER     : 38524-82-2
OTHER CAS REGISTRY NOS. : 57608-10-3
BEILSTEIN REFERENCE NO. : 2338086
LAST UPDATED            : 199806
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C11-H14-Cl3-O3-P-S
MOLECULAR WEIGHT        : 363.63
WISWESSER LINE NOTATION : GR CG EG BOPO&S3&O2
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * ENT 29118
   * O-Ethyl S-propyl O-(2,4,6-trichlorophenyl)phosphorothioate
   * RH-218
   * RH-8218
   * RH-28,218 Experimental Insecticide
   * Rohm & Haas RH-218
   * Trifenofos
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 uL/24H
REACTION SEVERITY       : Moderate
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535844
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 uL/24H
REACTION SEVERITY       : Mild
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535844
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 151 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of salivary glands
   Kidney, Ureter, Bladder - urine volume increased
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535389
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,35,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   6,85,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >2728 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,35,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 88 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Gastrointestinal - changes in structure or function of salivary glands
   Liver - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535844

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***