*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TC6592000
CHEMICAL NAME           : Phosphoric acid, mono(dichloropropyl) monooctyl ester
CAS REGISTRY NUMBER     : 117617-70-6
LAST UPDATED            : 199406
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H23-Cl2-O4-P
MOLECULAR WEIGHT        : 321.21
SYNONYMS/TRADE NAMES :
   * Octyl dichloropropyl phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10300 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(9),7,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7590 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(9),7,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(9),7,1988
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7980 mg/kg/6W-I
TOXIC EFFECTS :
   Cardiac - other changes
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - dehydrogenases
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 53(9),7,1988
 
                            *** END OF RECORD ***