*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TA2397400
CHEMICAL NAME           : Phosphonium,
                          (6,7,9,10,17,18,20,21-octahydrodibenzo(b,k)(1,4,7,10,
                          13,16)hexaoxacyclooct
                          adecin-2,14-diyl)bis(diphenyl(phenylmethyl)-,
                          dibromide
CAS REGISTRY NUMBER     : 134403-77-3
LAST UPDATED            : 199212
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C58-H56-O6-P2.2Br
MOLECULAR WEIGHT        : 1070.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4',4''(5'')-Bis(diphenylbenzylphosphonium)dibenzo-18-crown-6 dibromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 25,27,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 25,27,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 640 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 25,27,1991
 
                            *** END OF RECORD ***