*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TA1400000
CHEMICAL NAME : Phosphonic diamide,
p-(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)-N,N,N',N'-
tetramethyl-
CAS REGISTRY NUMBER : 1031-47-6
BEILSTEIN REFERENCE NO. : 0551608
REFERENCE : 5-26-08-00190 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C12-H19-N6-O-P
MOLECULAR WEIGHT : 294.34
WISWESSER LINE NOTATION : T5NN DNJ APON1&1&N1&1 CR& EZ
COMPOUND DESCRIPTOR : Agricultural Chemical
Reproductive Effector
SYNONYMS/TRADE NAMES :
* 5-Amino-1-bis(dimethylamide)phosphoryl-3-phenyl-1,2,4-triazole
* 5-Amino-1-(bis(dimethylamino)phosphinyl)-3-phenyl-1,2,4-triazole
* 5-Amino-1-bis(dimethylamido)phosphoryl-3-phenyl-1,2,4-triazole
* 5-Amino-3-fenil-1-bis(-dimetilamino)-fosforil-1,2,4-triazolo
* 5-Amino-3-fenyl-1-bis(dimethyl-amino)-fosforyl-1,2,4-triazool
* 5-Amino-3-phenyl-1-bis (dimethyl-amino)-phosphoryle-1,2,4-triazole
* 5-Amino-3-phenyl-1-bis(dimethylamino)-phosphoryl-1H-1,2,4-triazol
* 5-Amino-3-phenyl-1,2,4-triazole-1-yl-N,N,N',N'-tetramethylphosphodiamide
* 5-Amino-3-phenyl-1,2,4-triazolyl-1-bis(dimethylamido)pheosphate
* 5-Amino-3-phenyl-1,2,4-triazolylbis(dimethylamino)-phosphinoxid
* 5-Amino-3-phenyl-1,2,4-triazolyl-nnn'N'-tetramethyl-phosphonamide
* p-(5-Amino-3-phenyl-1H-1,2,4-triazol-1-yl)-N,N,N'-tetramethyl phosphonic
diamide
* Bis(dimethylamino)-3-amino-5-phenyltriazolyl phosphine oxide
* Niagara 5943
* 3-Phenyl-5-amino-1,2,4-triazolyl-(1)-(N,N'-tetramethyl)
diamidophosphonate
* Triamifos
* Triamiphos
* Triamphos
* Wepsin
* Wepsyn
* Wepsyn 155
* WP 155
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave.,
Willoughy, OH 44094) Volume(issue)/page/year: -,C325,1991
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 48 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71.
Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 15 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Lungs, Thorax, or Respiration - other changes
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB
211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year:
16,361,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
New York, Inc., 1971 Volume(issue)/page/year: -,427,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARSIM* Agricultural Research Service, USDA Information Memorandum.
(Beltsville, MD 20705) Volume(issue)/page/year: 20,27,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada,
171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,508,1973
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 1315 ug/kg
SEX/DURATION : multigenerations
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - hepatobiliary system
Reproductive - Specific Developmental Abnormalities - endocrine system
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 2,327,1974
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 6575 ug/kg
SEX/DURATION : multigenerations
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - blood and lymphatic
systems (including spleen and marrow)
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 2,327,1974
*** REVIEWS ***
TOXICOLOGY REVIEW
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44
Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year:
53,99,1974
*** END OF RECORD ***