*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SZ1830000
CHEMICAL NAME           : Phosphine oxide, tris(2,2-dimethyl-1-aziridinyl)-
CAS REGISTRY NUMBER     : 15312-14-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H24-N3-O-P
MOLECULAR WEIGHT        : 257.36
WISWESSER LINE NOTATION : T3NTJ B1 B1 APO&- AT3NTJ B1 B1&- AT3NTJ B1 B1
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * SK6231
   * TEPA-132
   * Tris(2,2-dimethyl-1-aziridinyl)phosphine oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Human
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   CCROBU Cancer Chemotherapy Reports, Part 1.  (Washington, DC)  V.52(6)-59,
   1968-75.  For publisher information, see CTRRDO.  Volume(issue)/page/year:
   56,393,1972
 
                            *** END OF RECORD ***