*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SZ8570000
CHEMICAL NAME : Phosphonic acid, (1-hydroxy-2,2,2-trichloroethyl)-,
diethyl ester
CAS REGISTRY NUMBER : 993-86-2
BEILSTEIN REFERENCE NO. : 1812867
REFERENCE : 4-01-00-03147 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C6-H12-Cl3-O4-P
MOLECULAR WEIGHT : 285.50
WISWESSER LINE NOTATION : GXGGYQPO&O2&O2
COMPOUND DESCRIPTOR : Agricultural Chemical
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Aethyltrichlorphon
* ETC
* Ethanephosphonic acid, 2,2,2-trichloro-1-hydroxy-, diethyl ester
* Ethyl trichlorfon
* Ethyltrichlorphon
* 1-Hydroxy-2,2,2-trichloroethyl diethyl phosphonite
* (1-Hydroxy-2,2,2-trichloroethyl)phosphonic acid diethyl ester
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB
Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem.
Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE : 240 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
REFERENCE :
ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB
Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem.
Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE : 960 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB
Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem.
Rep.) V.1- 1955- Volume(issue)/page/year: 22,565,1976
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - guinea pig
DOSE : 518 mg/kg
SEX/DURATION : female 42-44 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
NEREDZ Neurochemical Research. (Plenum Pub. Corp., 233 Spring St., New
York, NY 10013) V.1- 1976- Volume(issue)/page/year: 19,569,1994
*** END OF RECORD ***