*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SY8300000
CHEMICAL NAME           : Phosphinecarboxylic acid, dihydroxy-, oxide,
                          trisodium salt, hexahydrate
CAS REGISTRY NUMBER     : 34156-56-4
LAST UPDATED            : 199806
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C-H3-O5-P.3Na.6H2-O
SYNONYMS/TRADE NAMES :
   * Dihydroxyphosphinecarboxylic acid oxide trisodium salt hexahydrate
   * Foscarnet
   * Phosphonoformic acid, trisodium salt, hexahydrate
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8500 mg/kg/17D-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Blood - pigmented or nucleated red blood cells
   Blood - changes in erythrocyte (RBC) count
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   139,324,1996
 
                            *** END OF RECORD ***