*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO8650000
CHEMICAL NAME           : Phenothiazine, 10-(3-(dimethylamino)propyl)-,
                          phosphate
CAS REGISTRY NUMBER     : 1508-27-6
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H20-N2-S.xH3-O4-P
MOLECULAR WEIGHT        : 970.45
WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 &..H3.P-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10-(3-(Dimethylamino)propyl)phenothiazine phosphate
   * 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, phosphate
   * Promazine phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 123,78,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 151,515,1964
 
                            *** END OF RECORD ***