*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO7050000
CHEMICAL NAME           : Phenothiazine, 10-(3-(dimethylamino)propyl)-,
                          (E)-2-butenedioate
LAST UPDATED            : 198906
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H20-N2-S.C4-H4-O4
MOLECULAR WEIGHT        : 400.53
SYNONYMS/TRADE NAMES :
   * 10-(3-(Dimethylamino)propyl)phenothiazine (E)-2-butenedioate
   * Promazine fumarate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 141 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,295,1965
 
                            *** END OF RECORD ***