*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO5500000
CHEMICAL NAME           : Phenothiazine, 10-(2-(dimethylamino)-1-methylethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 5568-90-1
LAST UPDATED            : 199512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H20-N2-S.Cl-H
MOLECULAR WEIGHT        : 320.91
WISWESSER LINE NOTATION : T C666 BN ISJ BY1&1N1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Diprazin hydrochloride
   * N-(beta-Dimethylamino-alpha-methylethyl)phenothiazine hydrochloride
   * Isopromethazine hydrochloride
   * 10H-Phenothiazine-10-ethanamine, N,N,beta-trimethyl-, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Blood - hemorrhage
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 90,224,1947
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 95,428,1953
 
                            *** END OF RECORD ***