*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO5250000
CHEMICAL NAME           : Phenothiazine, 10-(2-(dimethylamino)ethyl)-
CAS REGISTRY NUMBER     : 522-24-7
LAST UPDATED            : 199506
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H18-N2-S
MOLECULAR WEIGHT        : 270.42
WISWESSER LINE NOTATION : T C666 BN ISJ B2N1&1
SYNONYMS/TRADE NAMES :
   * Anergell
   * Anergen
   * 10-(beta-Dimethylaminoethyl)phenothiazine
   * 10-(2-Dimethylaminoethyl)phenothiazine
   * N,N-Dimethyl-10H-phenothiazine-10-ethanamine
   * Ethizine
   * Ethysene
   * Ethysine
   * Ethyzine
   * Etisin
   * Etisine
   * Fenethazine
   * Lisergan
   * Lysergan
   * Parkazin
   * Phenetazine
   * Phenethazine
   * Phenethazinum
   * RP 3015
   * Rutergan
   * SC 1627
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 364 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 4,171,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 31,53,1968
 
                            *** END OF RECORD ***