*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SO0875000
CHEMICAL NAME           : Phenothiazine,
                          2-chloro-10-(3-(dimethylamino)propyl)-8-hydroxy-7-met
                          hoxy-
CAS REGISTRY NUMBER     : 21658-48-0
BEILSTEIN REFERENCE NO. : 1162953
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H21-Cl-N2-O2-S
MOLECULAR WEIGHT        : 364.92
WISWESSER LINE NOTATION : T C666 BN ISJ B3N1&1 EG MO1 NQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Hydroxy-7-methoxychlorpromazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 62,715,1973
 
                            *** END OF RECORD ***