*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SN7280000
CHEMICAL NAME           : Phenothiazine-10-carboxamide,
                          N-((1-ethyl-2-pyrrolidinyl)methyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 65274-45-5
LAST UPDATED            : 199707
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H23-N3-O-S.Cl-H
MOLECULAR WEIGHT        : 377.97
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chlorhydrate du  
   N-(N'-ethyl-pyrrolidino-2-methyl)-phenothiazine-10-carboxamide
   * N-((1-Ethyl-2-pyrrolidinyl)methyl)phenothiazine-10-carboxamide  
   monohydrochloride
   * F 1585
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 680 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   119,31,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRXXBL French Demande Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2326194
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRXXBL French Demande Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #2326194
 
                            *** END OF RECORD ***