*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BQ2680000
CHEMICAL NAME           : Ammonium,
                          (m-((1,3,2-dioxaphosphorinan-2-yl)oxy)phenyl)trimethy
                          l-, iodide, 2-oxide
CAS REGISTRY NUMBER     : 80531-03-9
LAST UPDATED            : 198906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H19-N-O4-P.I
MOLECULAR WEIGHT        : 399.19
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (m-((1,3,2-Dioxaphosphorinan-2-yl)oxy)phenyl)trimethylammonium iodide  
   2-oxide
   * TDPI
   * O-(3-(Trimethylammonio)phenyl)-1,3,2-dioxaphosphorinane 2-oxide iodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 327 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,145,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 444 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,145,1983
 
                            *** END OF RECORD ***