*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SL4956600
CHEMICAL NAME           : Phenol,
                          4-(1,2,3,5,8,8a-hexahydro-7-methyl-6-indolizinyl)-,
                          hydrobromide, monohydrate
LAST UPDATED            : 198912
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H19-N-O.Br-H.H2-O
MOLECULAR WEIGHT        : 328.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(1,2,3,5,8,8a-Hexahydro-7-methyl-6-indolizinyl)phenol hydrobromide  
   monohydrate
   * Ipalbidine hydrobromide hydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 189 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   CYLPDN Zhongguo Yaoli Xuebao.  Acta Pharmacologica Sinica.  Chinese Journal
   of Pharmacology.  (China International Book Trading Corp., POB 2820,
   Beijing, Peop. Rep. China)  V.1-    1980-  Volume(issue)/page/year:
   9,107,1988
 
                            *** END OF RECORD ***