*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SI7912000
CHEMICAL NAME           : Phenetole, beta-(ethylthio)-p-nitro-
CAS REGISTRY NUMBER     : 19594-18-4
BEILSTEIN REFERENCE NO. : 2971068
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H13-N-O3-S
MOLECULAR WEIGHT        : 227.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzene, 1-(2-(ethylthio)ethoxy)-4-nitro-
   * Synerphos
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 826 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 8,122,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 545 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 8,122,1973
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7517 mg/kg/26W-I
TOXIC EFFECTS :
   Liver - other changes
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   FATOBP Farmakologiya i Toksikologiya (Kiev).  Pharmacology and Toxicology.
   (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii,
   Kiev, USSR)  No.1-    1964-  Volume(issue)/page/year: 8,122,1973
 
                            *** END OF RECORD ***