*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SH6049000
CHEMICAL NAME           : Phenethylamine, N,alpha-dimethyl-N-2-propynyl-
CAS REGISTRY NUMBER     : 2323-36-6
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H17-N
MOLECULAR WEIGHT        : 187.31
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-
   * Deprenil
   * Deprenyl
   * N,alpha-Dimethyl-N-2-propynylbenzeneethanamine
   * N,alpha-Dimethyl-N-2-propynylphenethylamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 31,1253,1988
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 66 mg/kg
SEX/DURATION            : female 2-23 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   NEROEW Neuropsychopharmacology.  (Elsevier Science, 655 Avenue of the
   Americas, New York, NY  10010)  V.1-    1987-  Volume(issue)/page/year:
   11,125,1994
 
                            *** END OF RECORD ***