*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SH4955000
CHEMICAL NAME           : Phenethylamine, alpha,p-dimethyl-, hydrochloride,
                          (+-)-
CAS REGISTRY NUMBER     : 3706-37-4
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H15-N.Cl-H
MOLECULAR WEIGHT        : 185.72
WISWESSER LINE NOTATION : ZY1&1R D1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * dl-alpha,p-Dimethylphenethylamine hydrochloride
   * dl-p-Metil-alpha-metilfenetilamina HCl
   * dl-1-(4-Tolyl)-2-aminopropane hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,100,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 24,238,1969
 
                            *** END OF RECORD ***