*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SG1633000
CHEMICAL NAME           : Phenazinium,
                          3-(diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-p
                          henyl-, chloride
CAS REGISTRY NUMBER     : 2869-83-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C30-H31-N6.Cl
MOLECULAR WEIGHT        : 511.12
WISWESSER LINE NOTATION : T C666 BK INJ BR& ENUNR DN1&1& MN2&2 &G
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * C.I. 11050
   * 3-(Diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium  
   chloride
   * Janus Green B
   * Janus Green V
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 960 mg/kg/13W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   44,293,1953
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 20 umol/L/5H (Continuous)
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 1,27,1979

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1535
       No. of Facilities: 181 (estimated)
       No. of Industries: 5
       No. of Occupations: 5
       No. of Employees: 2102 (estimated)
       No. of Female Employees: 188 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***