*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SC9800000
CHEMICAL NAME           : Perchloric acid, sodium salt
CAS REGISTRY NUMBER     : 7601-89-0
LAST UPDATED            : 199701
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : Cl-O4.Na
MOLECULAR WEIGHT        : 122.44
WISWESSER LINE NOTATION :  NA  G-O4
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Natriumperchloraat
   * Natriumperchlorat
   * Perchlorate de sodium
   * Sodio (perclorato di)
   * Sodium (perchlorate de)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 17(8),33,1973
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 32,159,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 551 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
   (Paris, France)  V.1-261, 1835-1965.  For publisher information, see CRASEV.
    Volume(issue)/page/year: 257,791,1963
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 22500 mg/kg/45D-I
TOXIC EFFECTS :
   Liver - other changes
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - phosphatases
   Biochemical - Metabolism (Intermediary) - effect on mitochondrial function
REFERENCE :
   JEBIDP Journal of Environmental Biology.  (Academy of Environmental Biology,
   India, 657/5, Civil Lines (South), Muzaffarnagar, 251001, India) V.1-   
   1980-  Volume(issue)/page/year: 13,149,1992
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1500 pmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 21,171,1973

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - A1183
       No. of Facilities: 57 (estimated)
       No. of Industries: 2
       No. of Occupations: 2
       No. of Employees: 255 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - A1183
       No. of Facilities: 14 (estimated)
       No. of Industries: 2
       No. of Occupations: 2
       No. of Employees: 1452 (estimated)
       No. of Female Employees: 230 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***