*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SC6125000
CHEMICAL NAME           : Peppermint oil
CAS REGISTRY NUMBER     : 8006-90-4
LAST UPDATED            : 199701
DATA ITEMS CITED        : 8
COMPOUND DESCRIPTOR     : Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Pfefferminz oel
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2426 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,1071,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 819 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,1071,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2490 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOFOD5 Tokishikoroji Foramu.  Toxicology Forum.  (Saiensu Foramu, c/o Kida
   Bldg., 1-2-13 Yushima, Bunkyo-ku, Tokyo 113, Japan)  V.6-    1983-
   Volume(issue)/page/year: 8,91,1985
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9 gm/kg/90D-I
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 62,215,1992
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 5 uL/disc
REFERENCE :
   TOFOD5 Tokishikoroji Foramu.  Toxicology Forum.  (Saiensu Foramu, c/o Kida
   Bldg., 1-2-13 Yushima, Bunkyo-ku, Tokyo 113, Japan)  V.6-    1983-
   Volume(issue)/page/year: 8,91,1985

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80680
       No. of Facilities: 178 (estimated)
       No. of Industries: 7
       No. of Occupations: 26
       No. of Employees: 11237 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80680
       No. of Facilities: 2988 (estimated)
       No. of Industries: 46
       No. of Occupations: 55
       No. of Employees: 67045 (estimated)
       No. of Female Employees: 21627 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***