*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SA9350000
CHEMICAL NAME           : 2-Pentanone, 4-methyl-4-(N-nitrosomethylamino)-
CAS REGISTRY NUMBER     : 16339-21-2
BEILSTEIN REFERENCE NO. : 1765427
REFERENCE               : 3-04-00-00894 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H14-N2-O2
MOLECULAR WEIGHT        : 158.23
WISWESSER LINE NOTATION : ONN1&X1&1&1V1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Methyl-1,1-dimethylbutanon(3)-nitrosamin
   * 2-Methylnitrosamino-2-methylpentanon(4)
   * 4-Methyl-4-(N-nitrosomethylamino)-2-pentanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16 gm/kg/89W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967
 
                            *** END OF RECORD ***