*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SA0446000
CHEMICAL NAME           : Pentanedioic acid,
                          2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, dimethyl
                          ester, (S)-
CAS REGISTRY NUMBER     : 35457-98-8
LAST UPDATED            : 198912
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H15-N-O6
MOLECULAR WEIGHT        : 305.31
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (S)-2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)pentanedioic acid dimethyl  
   ester
   * N-Phthalyl-L-glutamic acid dimethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1700 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,647,1986
 
                            *** END OF RECORD ***