*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RY8450000
CHEMICAL NAME           : 1,4,5,6,8-Pentaazaacenaphthylen-3-amine,
                          1,5-dihydro-5-methyl-1-(5-O-phosphono-beta-D-
                          ribofuranosyl)-
CAS REGISTRY NUMBER     : 61966-08-3
LAST UPDATED            : 198605
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H17-N6-O7-P
MOLECULAR WEIGHT        : 400.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * NSC-280594
   * Pentaazaacenaphthylene-5' phosphate ester
   * Triciribine phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 193 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 109 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            *** END OF RECORD ***