*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RS2100000
CHEMICAL NAME           : Oxygen difluoride
CAS REGISTRY NUMBER     : 7783-41-7
LAST UPDATED            : 199712
DATA ITEMS CITED        : 20
MOLECULAR FORMULA       : F2-O
MOLECULAR WEIGHT        : 54.00
WISWESSER LINE NOTATION :  O   F2
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Fluorine monoxide
   * Fluorine oxide
   * Oxygen difluoride
   * Oxygen fluoride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 500 ppb
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,444,1969
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2600 ppb/1H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-70-77,1970
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 ppb/1H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-70-77,1970
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 26 ppm/1H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-70-77,1970
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 26 ppm/1H
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AMRL** Aerospace Medical Research Laboratory Report.  (Aerospace Technical
   Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
   Volume(issue)/page/year: TR-70-77,1970

                              *** REVIEWS ***
 
   ACGIH TLV-CL 0.11 mg/m3 (0.05 ppm)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.05 ppm (0.1 mg/m3)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,193,1971

   OSHA PEL (Gen Indu):8H TWA 0.05 ppm (0.1 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.05 ppm (0.1 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.05 ppm (0.1 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.05 ppm (0.1 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL-DENMARK:TWA 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL-FINLAND:STEL 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL-SWITZERLAND:TWA 0.05 ppm (0.1 mg/m3) JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO OXYGEN DIFLUORIDE-air:CL 0.05 ppm
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***