*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ5804000
CHEMICAL NAME           : 2-Oxazolin-4-one,
                          5-(1-indol-3-ylethyl)-2-(methylamino)-, (1R,5S)-(-)-
CAS REGISTRY NUMBER     : 21200-24-8
LAST UPDATED            : 198309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H16-N3-O2
MOLECULAR WEIGHT        : 258.33
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Indolmycin
   * (1R,5S)-(-)-5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one
   * PA-155-A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,127,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,128,1981
 
                            *** END OF RECORD ***