*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ5833560
CHEMICAL NAME           : 3H-Oxazolo(3,4-a)pyridine,
                          hexahydro-3-imino-1-(p-tolyl)-, hydrochloride, (Z)-
CAS REGISTRY NUMBER     : 5582-99-0
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N2-O.Cl-H
MOLECULAR WEIGHT        : 266.80
WISWESSER LINE NOTATION : T56 ANYOTJ BUM DR D1 -C &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * cis-3-Imino-1-(p-tolyl)hexahydro-3H-oxazolo(3,4-a)pyridine hydrochloride
   * (Z)-Hexahydro-3-imino-1-(p-tolyl)-3H-oxazolo(3,4-a)pyridine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
                            *** END OF RECORD ***