*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ5833400
CHEMICAL NAME           : 3H-Oxazolo(3,4-a)pyridine,
                          hexahydro-3-imino-1-phenyl-, hydrochloride, (E)-(-)-
CAS REGISTRY NUMBER     : 5712-25-4
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H16-N2-O.Cl-H
MOLECULAR WEIGHT        : 252.77
WISWESSER LINE NOTATION : T56 ANYOTJ BUM DR -L -T &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (-)-trans-3-Imino-hexahydro-1-phenyl-3H-oxazolo(3,4-a)pyridine,  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Autonomic Nervous System - sympathomimetic
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 13,127,1978
 
                            *** END OF RECORD ***