*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RQ2127000
CHEMICAL NAME           : 1,3-Oxazolidine, 2-methyl-3-nitroso-
CAS REGISTRY NUMBER     : 39884-53-2
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H8-N2-O2
MOLECULAR WEIGHT        : 116.14
WISWESSER LINE NOTATION : T5N COTJ ANO B1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Methyl-3-nitroso-1,3-oxazolidine
   * N-Nitroso-2-methyl-1,3-oxazolidine
   * Nitroso-2-methyl-1,3-oxazolidine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg/50W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Blood - leukemia
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 3,911,1982
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 500 ug/plate
REFERENCE :
   TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis.  (Alan R. Liss, Inc.,
   41 E. 11th St., New York, NY 10003)  V.1-    1980- Volume(issue)/page/year:
   1,295,1980
 
                            *** END OF RECORD ***