*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP7215000
CHEMICAL NAME           : Oxazolidine, 3,4-dimethyl-2-imino-5-phenyl-,
                          hydrobromide (E)-(+-)-
CAS REGISTRY NUMBER     : 75343-72-5
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H14-N2-O.Br-H
MOLECULAR WEIGHT        : 271.19
WISWESSER LINE NOTATION : T5MYOTJ A1 BUM DR& E1 -DL -T &EH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+-)-trans-3,4-Dimethyl-2-imino-5-phenyloxazolidine hydrobromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12500 ug/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
                            *** END OF RECORD ***