*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP6737600
CHEMICAL NAME           : 2H-1,5-Oxazocine-5(6H)-ethanol,
                          tetrahydro-alpha-(((1-methylethyl)amino)methyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 104317-86-4
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H26-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 303.32
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   Tetrahydro-alpha-(((1-methylethyl)amino)methyl)-2H-1,5-oxazocine-5(6H)-e
     thanol dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 42,489,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 42,489,1985
 
                            *** END OF RECORD ***