*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP6150000
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorine,
                          4,4'-dioxybis(2-(bis(2-chloroethyl)amino)tetrahydro-,
                          2,2'-dioxide
CAS REGISTRY NUMBER     : 67292-65-3
LAST UPDATED            : 198605
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H28-Cl4-N4-O6-P2
MOLECULAR WEIGHT        : 552.20
WISWESSER LINE NOTATION : T6MPOTJ BN2G2G FOO- FT6MPOTJ BN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4,4'-Dioxybis(2-(bis(2-chloroethyl)aminotetrahydro-2H-1,3,2-oxazaphospho
     rine))
   * 4-Hydroxycyclophosphamide anhydro-dimer
   * NSC 176986
   * 4-Peroxycyclophosphamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 263 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            *** END OF RECORD ***