*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP5789100
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorin-2-amine,
                          N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide, (S)-
CAS REGISTRY NUMBER     : 72282-85-0
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H18-Cl3-N2-O2-P
MOLECULAR WEIGHT        : 323.61
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (S)-N,N,3-Tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazophosphorin-2-amine  
   2-oxide
   * D-Trofosfamide
   * (+)-Trofosphamide
   * (S)-Trofosphamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   34,305,1986
 
                            *** END OF RECORD ***