*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP5789400
CHEMICAL NAME           : 2H-1,3,2-Oxazaphosphorin-2-amine,
                          tetrahydro-N-(2-bromoethyl)-3-(2-chloroethyl)-,
                          2-oxide, (+-)-
CAS REGISTRY NUMBER     : 146452-36-0
LAST UPDATED            : 199707
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H15-Br-Cl-N2-O2-P
MOLECULAR WEIGHT        : 305.57
SYNONYMS/TRADE NAMES :
   * KM 135
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 806 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 406 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IITOEF Immunopharmacology and Immunotoxicology.  (Marcel Dekker, 270 Madison
   Ave., New York, NY  10016)  V.9-    1987-  Volume(issue)/page/year:
   14,883,1992
 
                            *** END OF RECORD ***