*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP5787500
CHEMICAL NAME           : 1,3,2-Oxazaphospholidine,
                          2-(bis(2-chloroethyl)amino)-, 2-oxide
CAS REGISTRY NUMBER     : 5638-46-0
BEILSTEIN REFERENCE NO. : 0010536
REFERENCE               : 4-27-00-09749 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H13-Cl2-N2-O2-P
MOLECULAR WEIGHT        : 247.08
WISWESSER LINE NOTATION : T5MPOTJ BO BN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * B 485
   * N,N-Bis(beta-chloraethyl)-N',O-aethylenphosphorsaeure-ester-diamid
   * 2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphospholidine 2-oxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,143,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,1,1958
 
                            *** END OF RECORD ***