*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RP3720000
CHEMICAL NAME           : 3H,8H-4-Oxa-1-thia-9b-azacyclopenta(cd)phenalene-9-ca
                          rboxylic acid, 6-fluoro-5-(4-
                          methyl-1-piperazinyl)-8-oxo-, monohydrochloride
CAS REGISTRY NUMBER     : 119474-55-4
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H16-F-N3-O4-S.Cl-H
MOLECULAR WEIGHT        : 425.89
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * KB-5246
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1231 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 35,94,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 237 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 35,94,1992
 
                            *** END OF RECORD ***