*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RN6804000
CHEMICAL NAME           : 7-Oxa-3-azabicyclo(4.1.0)heptane, 3-nitroso-
CAS REGISTRY NUMBER     : 71785-87-0
BEILSTEIN REFERENCE NO. : 4733166
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H8-N2-O2
MOLECULAR WEIGHT        : 128.15
WISWESSER LINE NOTATION : T36 BO ENTJ ENO
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Nitroso-3,4-epoxypiperidine
   * 3-Nitroso-7-oxa-3-azabicyclo(4.1.0)heptane
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - angiosarcoma
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 1,753,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   TCMUE9 Topics in Chemical Mutagenesis.  (Plenum Pub. Corp., 233 Spring
   Street, New York, NY 10013) V.1-    1984-  Volume(issue)/page/year:
   1,13,1984
 
                            *** END OF RECORD ***