*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RO0412000
CHEMICAL NAME           : 1-Oxa-3,9-diazaspiro(5.5)undecan-2-one,
                          9-(3-(p-fluorobenzoyl)propyl)-5-phenyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 54981-18-9
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H27-F-N2-O3.Cl-H
MOLECULAR WEIGHT        : 446.99
WISWESSER LINE NOTATION : T6N CXTJ A3VR DF& C-& DT6MVOXTJ ER &GH
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 9,416,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 9,416,1974
 
                            *** END OF RECORD ***