*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : RG8400000
CHEMICAL NAME : Octane
CAS REGISTRY NUMBER : 111-65-9
LAST UPDATED : 199712
DATA ITEMS CITED : 36
MOLECULAR FORMULA : C8-H18
MOLECULAR WEIGHT : 114.26
WISWESSER LINE NOTATION : 8H
SYNONYMS/TRADE NAMES :
* n-Octane
* Octane
* Oktan
* Oktanen
* Ottani
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 118 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 32(10),23,1988
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 428 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
37,56,1975
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 mg/kg/7D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other oxidoreductases
REFERENCE :
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 22,271,1980
*** REVIEWS ***
ACGIH TLV-STEL 1750 mg/m3 (375 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 1400 mg/m3 (300 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 400 ppm (1900 mg/m3)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,191,1971
OSHA PEL (Gen Indu):8H TWA 500 ppm (2350 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 400 ppm (1900 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 400 ppm (1900 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 500 ppm (2350 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 300 ppm (1450 mg/m3);STEL 375 ppm (1800 mg/m3) JAN 1993
OEL-BELGIUM:TWA 300 ppm (1400 mg/m3);STEL 375 ppm (1750 mg/m3) JAN 1993
OEL-DENMARK:TWA 300 ppm (1450 mg/m3) JAN 1993
OEL-FINLAND:TWA 300 ppm (1400 mg/m3);STEL 375 ppm (1750 mg/m3) JAN 1993
OEL-FRANCE:TWA 300 ppm (1450 mg/m3) JAN 1993
OEL-GERMANY:TWA 500 ppm (2350 mg/m3) JAN 1993
OEL-HUNGARY:TWA 500 mg/m3;STEL 1500 mg/m3 JAN 1993
OEL-JAPAN:TWA 300 ppm (1400 mg/m3) JAN 1993
OEL-THE NETHERLANDS:TWA 300 ppm (1450 mg/m3) JAN 1993
OEL-THE PHILIPPINES:TWA 500 ppm (2350 mg/m3) JAN 1993
OEL-POLAND:TWA 200 mg/m3 JAN 1993
OEL-RUSSIA:TWA 300 ppm JAN 1993
OEL-SWEDEN:TWA 200 ppm (900 mg/m3);STEL 300 ppm (1400 mg/m3) JAN 1993
OEL-SWITZERLAND:TWA 300 ppm (1400 mg/m3);STEL 600 ppm JAN 1993
OEL-TURKEY:TWA 400 ppm (1900 mg/m3) JAN 1993
OEL-UNITED KINGDOM:TWA 300 ppm (1450 mg/m3);STEL 375 ppm JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO OCTANE-air:10H TWA 75 ppm;CL 385 ppm/15M
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 51705
No. of Facilities: 95 (estimated)
No. of Industries: 5
No. of Occupations: 8
No. of Employees: 940 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 51705
No. of Facilities: 1172 (estimated)
No. of Industries: 22
No. of Occupations: 18
No. of Employees: 9186 (estimated)
No. of Female Employees: 612 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NIOSH Analytical Method, 1994: Hydrocarbons, BP 36-126 degree C, 1500
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
*** END OF RECORD ***