*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : RG5830000
CHEMICAL NAME           : 2,6-Octadien-1-ol, 3,7-dimethyl-, (E)-
CAS REGISTRY NUMBER     : 106-24-1
BEILSTEIN REFERENCE NO. : 1722456
REFERENCE               : 4-01-00-02277 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 11
MOLECULAR FORMULA       : C10-H18-O
MOLECULAR WEIGHT        : 154.28
WISWESSER LINE NOTATION : Q2UY1&3UY1&1  -T
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * 2,6-Dimethyl-trans-2,6-octadien-8-ol
   * 3,7-Dimethyl-trans-2,6-octadien-1-ol
   * Geraniol
   * Geraniol alcohol
   * Geraniol Extra
   * Geranyl alcohol
   * Guaniol
   * Lemonol
   * 2,6-Octadien-1-ol, 3,7-dimethyl-, trans-
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 16 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   CTOIDG Cosmetics and Toiletries.  (Allured Pub. Corp., POB 318, Wheaton, IL
   60189)  V.91-    1976-  Volume(issue)/page/year: 94(8),41,1979
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
   Skin and Appendages - hair
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 2,327,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1090 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
REFERENCE :
   SIZSAR Sapporo Igaku Zasshi.  Sapporo Medical Journal.  (Sapporo Igaku
   Daigaku, Nishi-17-chome, Minami-1-jo, Chuo-ku, Sapporo 060, Japan)  V.3-
   1952-  Volume(issue)/page/year: 3,73,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JSICAZ Journal of Scientific and Industrial Research, Section C: Biological
   Sciences.  (New Delhi, India)  V.14-21, 1955-62.  For publisher information,
   see IJEBA6.  Volume(issue)/page/year: 21,342,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 12,881,1974
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   58,394,1962

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83197
       No. of Facilities: 169 (estimated)
       No. of Industries: 6
       No. of Occupations: 40
       No. of Employees: 10861 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83197
       No. of Facilities: 11902 (estimated)
       No. of Industries: 82
       No. of Occupations: 88
       No. of Employees: 192214 (estimated)
       No. of Female Employees: 104351 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***